Modeling Dynamic Cellular Morphology in Images

نویسندگان

  • Xing An
  • Zhiwen Liu
  • Yonggang Shi
  • Ning Li
  • Yalin Wang
  • Shantanu H. Joshi
چکیده

This paper presents a geometric method for modeling dynamic features of cells in image sequences. The morphological changes in cellular membrane boundaries are represented as sequences of parameterized contours. These sequences are analyzed as paths on a shape space equipped with an invariant metric, and matched using dynamic time warping. Experimental results show high sensitivity of the proposed dynamic features to the morphological changes observed in lymphocytes of healthy mice after undergoing skin transplantation when compared with standard representation methods and shape features.

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عنوان ژورنال:
  • Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention

دوره 15 Pt 1  شماره 

صفحات  -

تاریخ انتشار 2012